Advancements in Dermatology: A Weekly Review
Dermatologia e Venerologia
Acne Uncovered: Genetics, Metabolism, and the Future of Treatment
This episode takes a fresh look at acne vulgaris, one of the most common yet misunderstood skin conditions. We discuss groundbreaking genetic research, links to metabolic health, the role of isotretinoin on thyroid function, and promising new therapies ranging from blue light to stem-cell derivatives. Plus, practical findings on post-acne treatment options and how social media is reshaping dermatology research.
Bibliography
- Van Steensel MAM. The Genetics of Acne. Ann Hum Genet. 2025;89(5):333-41. doi:10.1111/ahg.70014. PMID: 40689430.
- Endres LM, Bungau AF, Tit DM, et al. Acne Vulgaris Associated with Metabolic Syndrome: Three-Case Series. Diagnostics (Basel). 2025;15(16):2018. doi:10.3390/diagnostics15162018. PMID: 40870870.
- Claudel JP, Ballanger F, Auffret N, et al. Obesity: A Modulator in Acne Management. Acta Derm Venereol. 2025;105:adv43945. doi:10.2340/actadv.v105.43945. PMID: 40842228.
- Kotb MA, Bin Dayel S, Abahussein O, et al. Isotretinoin Therapy and Thyroid Hormones: A Prospective Study. Medicine (Baltimore). 2025;104(35):e44236. doi:10.1097/MD.0000000000044236. PMID: 40898527.
- Werner A, Erkiert-Polguj A, Budzisz E. Blue Light in Skin: Anti-Inflammatory vs. Oxidative Stress. Biomed Pharmacother. 2025;191:118442. doi:10.1016/j.biopha.2025.118442. PMID: 40819541.
- Matwiejuk M, Mikłosz A, Myśliwiec H, et al. Adipose-Derived Stem Cells in Inflammatory Skin Diseases: Systematic Review. Front Immunol. 2025;16:1617157. doi:10.3389/fimmu.2025.1617157. PMID: 40918108.
- Ruchiatan K, Nuzuliyah G, Rizqandaru T, et al. Tranexamic Acid vs. Pulsed Dye Laser for Post-Acne Erythema: Split-Face Study. Clin Cosmet Investig Dermatol. 2025;18:2039-46. doi:10.2147/CCID.S538930. PMID: 40904413.
- Chen L, Ma Y, Cheng S, et al. Facial Malassezia Folliculitis After Infliximab in Crohn’s Disease: Case Report. Front Immunol. 2025;16:1611893. doi:10.3389/fimmu.2025.1611893. PMID: 40873576.
- Boxall C, Renz S, Stuart B, et al. Social Media Recruitment in Dermatology Trials: SAFA Study Findings. Trials. 2025;26(1):318. doi:10.1186/s13063-025-08994-5. PMID: 40866885.
