Advancements in Gastroenterology: A Weekly Review
Gastroenterologia
Gastroenterology Updates: From UC Management to Pancreatitis Subphenotypes
This week's episode covers groundbreaking research in gastroenterology, including ulcerative colitis management strategies, hepatitis C treatment outcomes, acute pancreatitis subphenotypes, and the gut-brain axis in autism spectrum disorder.
Bibliography
1. Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock.
Authors: Balamuth F, Weiss SL, Long E, et al.
Journal: The New England journal of medicine, 2026 Sep 3
PMID: 42028918
DOI: 10.1056/NEJMoa2601969
2. Sofosbuvir/Velpatasvir in Chronic Hepatitis C, Compensated and Decompensated Cirrhosis, and Retreatment Settings.
Authors: Takada H, Tamaki N, Ochi H, et al.
Journal: Internal medicine (Tokyo, Japan), 2026 Aug 15
PMID: 41485922
DOI: 10.2169/internalmedicine.6497-25
3. Splanchnic vein thrombosis with and without myeloproliferative neoplasms: a comparative cohort study.
Authors: Ko AK, Milana L, Riva N, et al.
Journal: Journal of thrombosis and haemostasis : JTH, 2026 Sep
PMID: 42173290
DOI: 10.1016/j.jtha.2026.05.014
4. Elevated microbially-derived metabolites in autism: a possible diagnostic screening test for a distinct ASD phenotype.
Authors: Flynn CK, Carr K, Whiteley P, et al.
Journal: Molecular psychiatry, 2026 Sep
PMID: 42192173
DOI: 10.1038/s41380-026-03620-5
5. Analysis of SLFN11 expression in small cell lung cancer, carcinoids and large cell neuroendocrine carcinoma: insights into lung neuroendocrine neoplasms.
Authors: Scattolin D, Heijboer FWJ, Pigato G, et al.
Journal: Lung cancer (Amsterdam, Netherlands), 2026 Sep
PMID: 42470748
DOI: 10.1016/j.lungcan.2026.109539
6. Cytomegalovirus Colitis during Budesonide Therapy for Ulcerative Colitis.
Authors: Tamazawa K, Aizawa M, Wada J, et al.
Journal: Internal medicine (Tokyo, Japan), 2026 Aug 15
PMID: 41535034
DOI: 10.2169/internalmedicine.6614-25
7. Effectiveness and safety of mirikizumab in multirefractory ulcerative colitis: analysis from a real-world cohort.
Authors: Melotti L, Monicelli O, Dussias NK, et al.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2026 Sep
PMID: 42401516
DOI: 10.1016/j.dld.2026.06.007
8. Development and validation of dynamic clinical subphenotypes for acute pancreatitis using hematocrit and blood urea nitrogen trajectories in intensive care unit: a multicenter retrospective cohort study.
Authors: Wan J, Kuang M, Xiong S, et al.
Journal: Journal of advanced research, 2026 Sep
PMID: 41485572
DOI: 10.1016/j.jare.2026.01.004
9. Anthropometric characteristics at birth and growth outcome in patients with X-linked hypophosphatemia treated with oral phosphate and active vitamin D.
Authors: Przygodda S, Brieger LC, Bohlen AV, et al.
Journal: Pediatric nephrology (Berlin, Germany), 2026 Sep
PMID: 41963716
DOI: 10.1007/s00467-026-07271-0
10. The Association of Faecal Calprotectin Measurements With Endo-Histological Remission in Ulcerative Colitis: A Pooled Analysis.
Authors: Dubé LR, Sorin M, Allez M, et al.
Journal: Alimentary pharmacology & therapeutics, 2026 Sep
PMID: 42227157
DOI: 10.1111/apt.70735
Authors: Balamuth F, Weiss SL, Long E, et al.
Journal: The New England journal of medicine, 2026 Sep 3
PMID: 42028918
DOI: 10.1056/NEJMoa2601969
2. Sofosbuvir/Velpatasvir in Chronic Hepatitis C, Compensated and Decompensated Cirrhosis, and Retreatment Settings.
Authors: Takada H, Tamaki N, Ochi H, et al.
Journal: Internal medicine (Tokyo, Japan), 2026 Aug 15
PMID: 41485922
DOI: 10.2169/internalmedicine.6497-25
3. Splanchnic vein thrombosis with and without myeloproliferative neoplasms: a comparative cohort study.
Authors: Ko AK, Milana L, Riva N, et al.
Journal: Journal of thrombosis and haemostasis : JTH, 2026 Sep
PMID: 42173290
DOI: 10.1016/j.jtha.2026.05.014
4. Elevated microbially-derived metabolites in autism: a possible diagnostic screening test for a distinct ASD phenotype.
Authors: Flynn CK, Carr K, Whiteley P, et al.
Journal: Molecular psychiatry, 2026 Sep
PMID: 42192173
DOI: 10.1038/s41380-026-03620-5
5. Analysis of SLFN11 expression in small cell lung cancer, carcinoids and large cell neuroendocrine carcinoma: insights into lung neuroendocrine neoplasms.
Authors: Scattolin D, Heijboer FWJ, Pigato G, et al.
Journal: Lung cancer (Amsterdam, Netherlands), 2026 Sep
PMID: 42470748
DOI: 10.1016/j.lungcan.2026.109539
6. Cytomegalovirus Colitis during Budesonide Therapy for Ulcerative Colitis.
Authors: Tamazawa K, Aizawa M, Wada J, et al.
Journal: Internal medicine (Tokyo, Japan), 2026 Aug 15
PMID: 41535034
DOI: 10.2169/internalmedicine.6614-25
7. Effectiveness and safety of mirikizumab in multirefractory ulcerative colitis: analysis from a real-world cohort.
Authors: Melotti L, Monicelli O, Dussias NK, et al.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2026 Sep
PMID: 42401516
DOI: 10.1016/j.dld.2026.06.007
8. Development and validation of dynamic clinical subphenotypes for acute pancreatitis using hematocrit and blood urea nitrogen trajectories in intensive care unit: a multicenter retrospective cohort study.
Authors: Wan J, Kuang M, Xiong S, et al.
Journal: Journal of advanced research, 2026 Sep
PMID: 41485572
DOI: 10.1016/j.jare.2026.01.004
9. Anthropometric characteristics at birth and growth outcome in patients with X-linked hypophosphatemia treated with oral phosphate and active vitamin D.
Authors: Przygodda S, Brieger LC, Bohlen AV, et al.
Journal: Pediatric nephrology (Berlin, Germany), 2026 Sep
PMID: 41963716
DOI: 10.1007/s00467-026-07271-0
10. The Association of Faecal Calprotectin Measurements With Endo-Histological Remission in Ulcerative Colitis: A Pooled Analysis.
Authors: Dubé LR, Sorin M, Allez M, et al.
Journal: Alimentary pharmacology & therapeutics, 2026 Sep
PMID: 42227157
DOI: 10.1111/apt.70735
