Advancements in Gastroenterology: A Weekly Review
Gastroenterologia
Gastroenterology Breakthroughs: From Gut Motility to Microbiota
This week we explore groundbreaking gastroenterology research, from genetic influences on gut motility to innovative approaches for liver metastases and microbiota-based therapies. Our experts discuss key clinical guidelines and diagnostic advances shaping modern GI practice.
Bibliography
1. Genetic dissection of stool frequency implicates vitamin B1 metabolism and other actionable pathways in the modulation of gut motility.
Authors: Díaz-Muñoz C, Bozzarelli I, Lopera-Maya EA, et al.
Journal: Gut
PMID: 41558814
DOI: 10.1136/gutjnl-2025-337059
2. Residual lipid risk in atherosclerotic cardiovascular disease.
Authors: Nordestgaard BG, Hegele RA
Journal: European heart journal
PMID: 41701506
DOI: 10.1093/eurheartj/ehag087
3. Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL-23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease.
Authors: Ooi CJ, Ling KL, Limsrivilai J, et al.
Journal: Journal of gastroenterology and hepatology
PMID: 42117726
DOI: 10.1111/jgh.70379
4. Intraperitoneal and Intravenous Paclitaxel Plus S-1 for Gastric Cancer With Peritoneal Metastasis: A Phase 3 Randomized Clinical Trial.
Authors: Yan C, Yang Z, Shi Z, et al.
Journal: JAMA oncology
PMID: 42166134
DOI: 10.1001/jamaoncol.2026.1347
5. Associations between demographic, clinical and dietary factors and flares in inflammatory bowel disease: the PRognostic effect of Environmental factors in Crohn's and Colitis (PREdiCCt) prospective cohort study.
Authors: Constantine-Cooke N, Gros B, Plevris N, et al.
Journal: Gut
PMID: 41554630
DOI: 10.1136/gutjnl-2025-337846
6. Clinical Trial Endpoints for Perianal Fistulizing Crohn's Disease.
Authors: Reinisch W, Atreya R, Rieder F, et al.
Journal: The American journal of gastroenterology
PMID: 41504318
DOI: 10.14309/ajg.0000000000003906
7. Colorectal cancer liver metastases: mechanism and therapy.
Authors: Liu S, Ban L, Zhang W, et al.
Journal: Frontiers in immunology
PMID: 42500682
DOI: 10.3389/fimmu.2026.1861130
8. Gut microbiota in health and disease.
Authors: Li Y, Xiao X, Jiang X, et al.
Journal: Molecular biomedicine
PMID: 42474869
DOI: 10.1186/s43556-026-00512-6
9. Budd-Chiari Syndrome: Presentation, Management, and Prognosis.
Authors: Amjad W, Thuluvath PJ
Journal: The American journal of gastroenterology
PMID: 41384820
DOI: 10.14309/ajg.0000000000003886
10. Performance Evaluation of the Xpert® HCV Test on Fingerstick Blood in a Prospective Observational Clinical Study at CLIA-Waived Sites in the United States.
Authors: Havens JR, Fluker SA, Schimmel J, et al.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
PMID: 41823658
DOI: 10.1093/cid/ciag173
Authors: Díaz-Muñoz C, Bozzarelli I, Lopera-Maya EA, et al.
Journal: Gut
PMID: 41558814
DOI: 10.1136/gutjnl-2025-337059
2. Residual lipid risk in atherosclerotic cardiovascular disease.
Authors: Nordestgaard BG, Hegele RA
Journal: European heart journal
PMID: 41701506
DOI: 10.1093/eurheartj/ehag087
3. Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL-23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease.
Authors: Ooi CJ, Ling KL, Limsrivilai J, et al.
Journal: Journal of gastroenterology and hepatology
PMID: 42117726
DOI: 10.1111/jgh.70379
4. Intraperitoneal and Intravenous Paclitaxel Plus S-1 for Gastric Cancer With Peritoneal Metastasis: A Phase 3 Randomized Clinical Trial.
Authors: Yan C, Yang Z, Shi Z, et al.
Journal: JAMA oncology
PMID: 42166134
DOI: 10.1001/jamaoncol.2026.1347
5. Associations between demographic, clinical and dietary factors and flares in inflammatory bowel disease: the PRognostic effect of Environmental factors in Crohn's and Colitis (PREdiCCt) prospective cohort study.
Authors: Constantine-Cooke N, Gros B, Plevris N, et al.
Journal: Gut
PMID: 41554630
DOI: 10.1136/gutjnl-2025-337846
6. Clinical Trial Endpoints for Perianal Fistulizing Crohn's Disease.
Authors: Reinisch W, Atreya R, Rieder F, et al.
Journal: The American journal of gastroenterology
PMID: 41504318
DOI: 10.14309/ajg.0000000000003906
7. Colorectal cancer liver metastases: mechanism and therapy.
Authors: Liu S, Ban L, Zhang W, et al.
Journal: Frontiers in immunology
PMID: 42500682
DOI: 10.3389/fimmu.2026.1861130
8. Gut microbiota in health and disease.
Authors: Li Y, Xiao X, Jiang X, et al.
Journal: Molecular biomedicine
PMID: 42474869
DOI: 10.1186/s43556-026-00512-6
9. Budd-Chiari Syndrome: Presentation, Management, and Prognosis.
Authors: Amjad W, Thuluvath PJ
Journal: The American journal of gastroenterology
PMID: 41384820
DOI: 10.14309/ajg.0000000000003886
10. Performance Evaluation of the Xpert® HCV Test on Fingerstick Blood in a Prospective Observational Clinical Study at CLIA-Waived Sites in the United States.
Authors: Havens JR, Fluker SA, Schimmel J, et al.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
PMID: 41823658
DOI: 10.1093/cid/ciag173
