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Advances in Nephrology and Beyond: From CKD Management to Post-COVID Microvascular Changes

Inside Nephrology: A Weekly Review

Nefrologia

Advances in Nephrology and Beyond: From CKD Management to Post-COVID Microvascular Changes

This week we cover groundbreaking research in nephrology and beyond, from combination therapy for CKD to post-COVID microvascular changes and XLH growth outcomes. Join us as we discuss these important clinical advances with expert analysis.

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Bibliografia

1. Safety and Synergy of Finerenone and Empagliflozin in Lowering Blood Pressure.
Authors: Agarwal R, Correa-Rotter R, Navaneethan SD, et al.
Journal: Hypertension (Dallas, Tex. : 1979), 2026 Sep
PMID: 42244376
DOI: 10.1161/HYPERTENSIONAHA.126.27036


2. Natural History of C3 Glomerulopathy and Immune Complex-Associated Membranoproliferative Glomerulonephritis in Children.
Authors: Dixon BP, Laskin BL, Goodwin Davies AJ, et al.
Journal: Clinical journal of the American Society of Nephrology : CJASN, 2026 Sep 1
PMID: 42329702
DOI: 10.2215/CJN.0000001118


3. Anthropometric characteristics at birth and growth outcome in patients with X-linked hypophosphatemia treated with oral phosphate and active vitamin D.
Authors: Przygodda S, Brieger LC, Bohlen AV, et al.
Journal: Pediatric nephrology (Berlin, Germany), 2026 Sep
PMID: 41963716
DOI: 10.1007/s00467-026-07271-0


4. Low-Dose Fisetin Supplementation and Its Association With Chronic Inflammation in Middle-Aged and Older Adults: Study Protocol for a Triple-Blind, Randomised, Placebo-Controlled Trial.
Authors: Tavenier J, Berglind M, Hach LF, et al.
Journal: Basic & clinical pharmacology & toxicology, 2026 Sep
PMID: 42633989
DOI: 10.1111/bcpt.70290


5. A randomized controlled trial comparing en-bloc vs lobe-by-lobe HoLEP: surgical efficiency and early continence outcomes.
Authors: Elmorsy YH, Elshal AM, El-Nahas AR, et al.
Journal: Prostate cancer and prostatic diseases, 2026 Sep
PMID: 41198920
DOI: 10.1038/s41391-025-01040-0


6. Early predictors of MR4.5 attainment and eligibility for TKI discontinuation in CML treated with second-generation TKIs.
Authors: Ono T, Okada T, Takahashi N, et al.
Journal: Blood advances, 2026 Aug 25
PMID: 42275565
DOI: 10.1182/bloodadvances.2026019701


7. Sustained improvement in renal function with palopegteriparatide in adults with chronic hypoparathyroidism: 2-year results from the phase 3 PaTHway-trial.
Authors: Rejnmark L, Gosmanova EO, Khan AA, et al.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2026 Aug 21
PMID: 42166177
DOI: 10.1093/jbmr/zjag085


8. European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) steatotic liver disease special interest group position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction-associated steatotic liver disease.
Authors: Mann JP, Lefere S, Buytaert M, et al.
Journal: Journal of pediatric gastroenterology and nutrition, 2026 Sep
PMID: 42374900
DOI: 10.1002/jpn3.70490


9. Microvascular remodeling and endothelial dysfunction across the post-COVID-19 spectrum: a prospective observational case-control study.
Authors: Wallraven T, Günthner R, Lethen I, et al.
Journal: BMC medicine, 2026 Aug 19
PMID: 42625188
DOI: 10.1186/s12916-026-05144-9


10. Upadacitinib monotherapy versus methotrexate monotherapy in methotrexate-naïve Japanese patients with rheumatoid arthritis: Long-term efficacy and safety through 5 years in the SELECT-EARLY study.
Authors: Takeuchi T, van Vollenhoven R, Ueki Y, et al.
Journal: Modern rheumatology, 2026 Aug 31
PMID: 41967478
DOI: 10.1093/mr/roag031

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