Pediatric Frontiers: Weekly Insights
Pediatria
Advances in Pediatric Immunology and Neonatal Care
This week we explore groundbreaking research in pediatric immunology, neonatal nutrition, and innovative therapies for preterm infants, featuring studies on food allergy genetics, RSV prevention, and mesenchymal stromal cells for BPD.
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Bibliografia
1. Meta-analysis of genome-wide association studies of food allergy and IgE sensitization.
Authors: Maier L, Sun Y, Kronberg J, et al.
Journal: The Journal of allergy and clinical immunology, 2026 Jul
PMID: 41724405
DOI: 10.1016/j.jaci.2026.02.012
2. Nirsevimab Immunization to Prevent Pediatric RSV Hospitalizations.
Authors: Attaianese F, Carreras G, Trapani S, et al.
Journal: JAMA pediatrics, 2026 Jul 1
PMID: 41973439
DOI: 10.1001/jamapediatrics.2026.0657
3. Impact of early parenteral amino acid on preterm infant: A multicenter study.
Authors: Lin YY, Chen CH, Tsai ML, et al.
Journal: Pediatrics and neonatology, 2026 Jul
PMID: 41535213
DOI: 10.1016/j.pedneo.2025.11.008
4. Helping Underdeveloped Lungs with Cells (HULC-2): mesenchymal stromal cells in extreme preterm infants at risk of developing bronchopulmonary dysplasia - a study protocol of a phase 2 multicentre double blind randomised controlled trial in Canada.
Authors: Renesme L, Ferretti E, Horth C, et al.
Journal: BMJ open, 2026 Jul 6
PMID: 42409407
DOI: 10.1136/bmjopen-2025-112385
5. Probiotics, Prebiotics, Lactoferrin, and Combination Products for Prevention of Mortality and Morbidity in Preterm Infants: A Systematic Review and Network Meta-Analysis.
Authors: Wang Y, Florez ID, Morgan RL, et al.
Journal: JAMA pediatrics, 2023 Nov 1
PMID: 37782505
DOI: 10.1001/jamapediatrics.2023.3849
6. MEN1 mutations mediate clinical resistance to menin inhibition.
Authors: Perner F, Stein EM, Wenge DV, et al.
Journal: Nature, 2023 Mar
PMID: 36922589
DOI: 10.1038/s41586-023-05755-9
7. Prevalence of pain and fear as barriers to vaccination in children - Systematic review and meta-analysis.
Authors: Taddio A, McMurtry CM, Logeman C, et al.
Journal: Vaccine, 2022 Dec 12
PMID: 36283899
DOI: 10.1016/j.vaccine.2022.10.026
8. Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis.
Authors: Locatelli F, Jordan MB, Allen C, et al.
Journal: The New England journal of medicine, 2020 May 7
PMID: 32374962
DOI: 10.1056/NEJMoa1911326
9. Updates in Late-Onset Sepsis: Risk Assessment, Therapy, and Outcomes.
Authors: Coggins SA, Glaser K
Journal: NeoReviews, 2022 Nov 1
PMID: 36316254
DOI: 10.1542/neo.23-10-e738
Authors: Maier L, Sun Y, Kronberg J, et al.
Journal: The Journal of allergy and clinical immunology, 2026 Jul
PMID: 41724405
DOI: 10.1016/j.jaci.2026.02.012
2. Nirsevimab Immunization to Prevent Pediatric RSV Hospitalizations.
Authors: Attaianese F, Carreras G, Trapani S, et al.
Journal: JAMA pediatrics, 2026 Jul 1
PMID: 41973439
DOI: 10.1001/jamapediatrics.2026.0657
3. Impact of early parenteral amino acid on preterm infant: A multicenter study.
Authors: Lin YY, Chen CH, Tsai ML, et al.
Journal: Pediatrics and neonatology, 2026 Jul
PMID: 41535213
DOI: 10.1016/j.pedneo.2025.11.008
4. Helping Underdeveloped Lungs with Cells (HULC-2): mesenchymal stromal cells in extreme preterm infants at risk of developing bronchopulmonary dysplasia - a study protocol of a phase 2 multicentre double blind randomised controlled trial in Canada.
Authors: Renesme L, Ferretti E, Horth C, et al.
Journal: BMJ open, 2026 Jul 6
PMID: 42409407
DOI: 10.1136/bmjopen-2025-112385
5. Probiotics, Prebiotics, Lactoferrin, and Combination Products for Prevention of Mortality and Morbidity in Preterm Infants: A Systematic Review and Network Meta-Analysis.
Authors: Wang Y, Florez ID, Morgan RL, et al.
Journal: JAMA pediatrics, 2023 Nov 1
PMID: 37782505
DOI: 10.1001/jamapediatrics.2023.3849
6. MEN1 mutations mediate clinical resistance to menin inhibition.
Authors: Perner F, Stein EM, Wenge DV, et al.
Journal: Nature, 2023 Mar
PMID: 36922589
DOI: 10.1038/s41586-023-05755-9
7. Prevalence of pain and fear as barriers to vaccination in children - Systematic review and meta-analysis.
Authors: Taddio A, McMurtry CM, Logeman C, et al.
Journal: Vaccine, 2022 Dec 12
PMID: 36283899
DOI: 10.1016/j.vaccine.2022.10.026
8. Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis.
Authors: Locatelli F, Jordan MB, Allen C, et al.
Journal: The New England journal of medicine, 2020 May 7
PMID: 32374962
DOI: 10.1056/NEJMoa1911326
9. Updates in Late-Onset Sepsis: Risk Assessment, Therapy, and Outcomes.
Authors: Coggins SA, Glaser K
Journal: NeoReviews, 2022 Nov 1
PMID: 36316254
DOI: 10.1542/neo.23-10-e738
