Advancements in Gastroenterology: A Weekly Review
Gastroenterologia
Advances in Gastroenterology and Hepatology
This episode covers recent advances in gastroenterology and hepatology, including updates on Behçet's syndrome management, HCV screening strategies, alcohol-related cirrhosis, IBD pathogenesis, dietary interventions for IBS, and novel cancer treatments.
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Bibliografia
1. EULAR recommendations for the management of Behçet's syndrome: 2025 update.
Authors: Hatemi G, Ramiro S, Ozguler Y, et al.
Journal: Annals of the rheumatic diseases, 2026 Jun
PMID: 41876291
DOI: 10.1016/j.ard.2026.02.009
2. Hepatitis C Screening in Emergency Departments: The DETECT Hep C Randomized Clinical Trial.
Authors: Haukoos J, Rothman RE, Galbraith JW, et al.
Journal: JAMA, 2025 Aug 12
PMID: 40632510
DOI: 10.1001/jama.2025.10563
3. Incidence and implications of abstinence-induced recompensation in alcohol-related cirrhosis.
Authors: Hofer BS, Tonon M, Buttler L, et al.
Journal: Journal of hepatology, 2026 Jun
PMID: 41580090
DOI: 10.1016/j.jhep.2026.01.007
4. Efficacy and safety of upadacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis.
Authors: Xu YH, Liu D, Zhang MR, et al.
Journal: Frontiers in immunology, 2026
PMID: 42245676
DOI: 10.3389/fimmu.2026.1806265
5. Efficacy of dietary interventions in irritable bowel syndrome: a systematic review and network meta-analysis.
Authors: Cuffe MS, Staudacher HM, Aziz I, et al.
Journal: The lancet. Gastroenterology & hepatology, 2025 Jun
PMID: 40258374
DOI: 10.1016/S2468-1253(25)00054-8
6. Inflammatory Bowel Diseases and Gut Microbiota.
Authors: Haneishi Y, Furuya Y, Hasegawa M, et al.
Journal: International journal of molecular sciences, 2023 Feb 14
PMID: 36835245
DOI: 10.3390/ijms24043817
7. Encorafenib, Cetuximab, and mFOLFOX6 in BRAF-Mutated Colorectal Cancer.
Authors: Elez E, Yoshino T, Shen L, et al.
Journal: The New England journal of medicine, 2025 Jun 26
PMID: 40444708
DOI: 10.1056/NEJMoa2501912
8. Genetics, Cell Biology, and Pathophysiology of Pancreatitis.
Authors: Mayerle J, Sendler M, Hegyi E, et al.
Journal: Gastroenterology, 2019 May
PMID: 30660731
DOI: 10.1053/j.gastro.2018.11.081
9. The many pathways driving liver inflammation in MASH.
Authors: Tilg H, Adolph TE, Romeo S, et al.
Journal: Cell metabolism, 2026 Jun 2
PMID: 41875884
DOI: 10.1016/j.cmet.2026.02.018
10. A multicenter dose-defining/expansion phase 1b study of first-line regorafenib plus pembrolizumab in patients with advanced hepatocellular carcinoma.
Authors: El-Khoueiry AB, Kim RD, Harris WP, et al.
Journal: Hepatology (Baltimore, Md.), 2026 Jun 1
PMID: 41213032
DOI: 10.1097/HEP.0000000000001585
Authors: Hatemi G, Ramiro S, Ozguler Y, et al.
Journal: Annals of the rheumatic diseases, 2026 Jun
PMID: 41876291
DOI: 10.1016/j.ard.2026.02.009
2. Hepatitis C Screening in Emergency Departments: The DETECT Hep C Randomized Clinical Trial.
Authors: Haukoos J, Rothman RE, Galbraith JW, et al.
Journal: JAMA, 2025 Aug 12
PMID: 40632510
DOI: 10.1001/jama.2025.10563
3. Incidence and implications of abstinence-induced recompensation in alcohol-related cirrhosis.
Authors: Hofer BS, Tonon M, Buttler L, et al.
Journal: Journal of hepatology, 2026 Jun
PMID: 41580090
DOI: 10.1016/j.jhep.2026.01.007
4. Efficacy and safety of upadacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis.
Authors: Xu YH, Liu D, Zhang MR, et al.
Journal: Frontiers in immunology, 2026
PMID: 42245676
DOI: 10.3389/fimmu.2026.1806265
5. Efficacy of dietary interventions in irritable bowel syndrome: a systematic review and network meta-analysis.
Authors: Cuffe MS, Staudacher HM, Aziz I, et al.
Journal: The lancet. Gastroenterology & hepatology, 2025 Jun
PMID: 40258374
DOI: 10.1016/S2468-1253(25)00054-8
6. Inflammatory Bowel Diseases and Gut Microbiota.
Authors: Haneishi Y, Furuya Y, Hasegawa M, et al.
Journal: International journal of molecular sciences, 2023 Feb 14
PMID: 36835245
DOI: 10.3390/ijms24043817
7. Encorafenib, Cetuximab, and mFOLFOX6 in BRAF-Mutated Colorectal Cancer.
Authors: Elez E, Yoshino T, Shen L, et al.
Journal: The New England journal of medicine, 2025 Jun 26
PMID: 40444708
DOI: 10.1056/NEJMoa2501912
8. Genetics, Cell Biology, and Pathophysiology of Pancreatitis.
Authors: Mayerle J, Sendler M, Hegyi E, et al.
Journal: Gastroenterology, 2019 May
PMID: 30660731
DOI: 10.1053/j.gastro.2018.11.081
9. The many pathways driving liver inflammation in MASH.
Authors: Tilg H, Adolph TE, Romeo S, et al.
Journal: Cell metabolism, 2026 Jun 2
PMID: 41875884
DOI: 10.1016/j.cmet.2026.02.018
10. A multicenter dose-defining/expansion phase 1b study of first-line regorafenib plus pembrolizumab in patients with advanced hepatocellular carcinoma.
Authors: El-Khoueiry AB, Kim RD, Harris WP, et al.
Journal: Hepatology (Baltimore, Md.), 2026 Jun 1
PMID: 41213032
DOI: 10.1097/HEP.0000000000001585
