Advancements in Gastroenterology: A Weekly Review
Gastroenterologia
Gut Microbiome Modulation and IBD Advances
This week's episode covers groundbreaking research on gut microbiome modulation in transplant patients, advances in IBD treatment strategies, and new guidelines for biliary stricture management. We discuss key findings from recent studies on human milk oligosaccharides, capsule endoscopy in Crohn's disease, and diagnostic models for sclerosing cholangitis.
Bibliography
1. Human milk oligosaccharide (2'-FL) modifies the gut microbiome in children after bone marrow transplant.
Authors: Ramos KN, Langenberg L, Lake KE, et al.
Journal: Blood, 2026 Oct 29
PMID: 42622257
DOI: 10.1182/blood.2026034172
2. From mice to humans-divergent strategies for intestinal homeostasis and regeneration.
Authors: Ishikawa K, Sugimoto S, Sato T
Journal: FEBS letters, 2026 Nov
PMID: 42317040
DOI: 10.1002/1873-3468.70387
3. Influence of Albumin Treatment Duration on Outcome of Terlipressin Therapy in Patients With HRS-AKI.
Authors: Schleicher EM, Labenz C, Uschner FE, et al.
Journal: Liver international : official journal of the International Association for the Study of the Liver, 2026 Nov
PMID: 42813964
DOI: 10.1111/liv.70888
4. From guidelines to precision care: How contemporary evidence is transforming IPMN management.
Authors: Ricci C, Signoretti M, Goni E, et al.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2026 Nov
PMID: 42527223
DOI: 10.1016/j.dld.2026.06.020
5. Biliary stricture management: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Authors: Lemmers A, Tringali A, Teles de Campos S, et al.
Journal: Endoscopy, 2026 Nov
PMID: 42692059
DOI: 10.1055/a-2921-6492
6. Computational fluid dynamics for severity assessment of arterial occlusive diseases.
Authors: Li W, Tan Y, van der Doef HPJ, et al.
Journal: European journal of radiology, 2026 Nov
PMID: 42470755
DOI: 10.1016/j.ejrad.2026.113087
7. TL1A-DR3 Signaling in Inflammatory Bowel Disease: From Pathogenesis to Therapeutic Targeting.
Authors: Tsuruta K, Yoshioka S, Takedatsu H
Journal: The Kurume medical journal, 2026 Nov 11
PMID: 42633936
DOI: 10.2739/kurumemedj.MS7312004
8. Capsule endoscopy for treat-to-target monitoring in Crohn's disease: a systematic review and meta-analysis.
Authors: Marmo C, Puca FS, McNamara D, et al.
Journal: Gastrointestinal endoscopy, 2026 Nov
PMID: 42349762
DOI: 10.1016/j.gie.2026.06.031
9. Atezolizumab-bevacizumab with or without cisplatin-based HAIC for unresectable HCC: A randomized phase II trial.
Authors: Takeuchi Y, Sue M, Miyake N, et al.
Journal: JHEP reports : innovation in hepatology, 2026 Nov
PMID: 42665190
DOI: 10.1016/j.jhepr.2026.102002
10. PSC-DM: A Validated Clinical Diagnostic Model for Distinguishing Primary From Secondary Sclerosing Cholangitis.
Authors: Scaravaglio M, Motta RV, Cristoferi L, et al.
Journal: Liver international : official journal of the International Association for the Study of the Liver, 2026 Nov
PMID: 42813454
DOI: 10.1111/liv.70892
Authors: Ramos KN, Langenberg L, Lake KE, et al.
Journal: Blood, 2026 Oct 29
PMID: 42622257
DOI: 10.1182/blood.2026034172
2. From mice to humans-divergent strategies for intestinal homeostasis and regeneration.
Authors: Ishikawa K, Sugimoto S, Sato T
Journal: FEBS letters, 2026 Nov
PMID: 42317040
DOI: 10.1002/1873-3468.70387
3. Influence of Albumin Treatment Duration on Outcome of Terlipressin Therapy in Patients With HRS-AKI.
Authors: Schleicher EM, Labenz C, Uschner FE, et al.
Journal: Liver international : official journal of the International Association for the Study of the Liver, 2026 Nov
PMID: 42813964
DOI: 10.1111/liv.70888
4. From guidelines to precision care: How contemporary evidence is transforming IPMN management.
Authors: Ricci C, Signoretti M, Goni E, et al.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2026 Nov
PMID: 42527223
DOI: 10.1016/j.dld.2026.06.020
5. Biliary stricture management: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Authors: Lemmers A, Tringali A, Teles de Campos S, et al.
Journal: Endoscopy, 2026 Nov
PMID: 42692059
DOI: 10.1055/a-2921-6492
6. Computational fluid dynamics for severity assessment of arterial occlusive diseases.
Authors: Li W, Tan Y, van der Doef HPJ, et al.
Journal: European journal of radiology, 2026 Nov
PMID: 42470755
DOI: 10.1016/j.ejrad.2026.113087
7. TL1A-DR3 Signaling in Inflammatory Bowel Disease: From Pathogenesis to Therapeutic Targeting.
Authors: Tsuruta K, Yoshioka S, Takedatsu H
Journal: The Kurume medical journal, 2026 Nov 11
PMID: 42633936
DOI: 10.2739/kurumemedj.MS7312004
8. Capsule endoscopy for treat-to-target monitoring in Crohn's disease: a systematic review and meta-analysis.
Authors: Marmo C, Puca FS, McNamara D, et al.
Journal: Gastrointestinal endoscopy, 2026 Nov
PMID: 42349762
DOI: 10.1016/j.gie.2026.06.031
9. Atezolizumab-bevacizumab with or without cisplatin-based HAIC for unresectable HCC: A randomized phase II trial.
Authors: Takeuchi Y, Sue M, Miyake N, et al.
Journal: JHEP reports : innovation in hepatology, 2026 Nov
PMID: 42665190
DOI: 10.1016/j.jhepr.2026.102002
10. PSC-DM: A Validated Clinical Diagnostic Model for Distinguishing Primary From Secondary Sclerosing Cholangitis.
Authors: Scaravaglio M, Motta RV, Cristoferi L, et al.
Journal: Liver international : official journal of the International Association for the Study of the Liver, 2026 Nov
PMID: 42813454
DOI: 10.1111/liv.70892
