Advancements in Gynecology: A Weekly Review
Ginecologia e Ostetricia
Advances in Maternal-Fetal Medicine and Gynecologic Oncology
This week we discuss important findings in maternal-fetal medicine including diabetes in pregnancy, preeclampsia prevention, and eclampsia management, plus updates in gynecologic oncology including new treatment options for endometrial cancer and cervical cancer standards.
Bibliography
1. A Systematic Review to Compare Adverse Pregnancy Outcomes in Women with Pregestational Diabetes and Gestational Diabetes.
Authors: Malaza N, Masete M, Adam S, et al.
Journal: International journal of environmental research and public health, 2022 Aug 31
PMID: 36078559
DOI: 10.3390/ijerph191710846
2. Nutritional supplements for preventing preeclampsia: A network meta-analysis.
Authors: Wang C, You C, Zhang Y
Journal: The Indian journal of medical research, 2026 Jul
PMID: 42397815
DOI: 10.25259/IJMR_1582_2025
3. Impact of Oral Sebetralstat on Anxiety Associated With Hereditary Angioedema Attacks.
Authors: Craig T, Aygören-Pürsün E, Bernstein JA, et al.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2026 Jul
PMID: 41786301
DOI: 10.1111/cea.70241
4. ULK1's role in cancer progression and its emerging therapeutic potential.
Authors: Webb JD, Shepherd TG
Journal: Cancer biology & therapy, 2026 Dec 31
PMID: 42308349
DOI: 10.1080/15384047.2026.2680347
5. Adjuvant chemotherapy following chemoradiotherapy as primary treatment for locally advanced cervical cancer versus chemoradiotherapy alone (OUTBACK): an international, open-label, randomised, phase 3 trial.
Authors: Mileshkin LR, Moore KN, Barnes EH, et al.
Journal: The Lancet. Oncology, 2023 May
PMID: 37080223
DOI: 10.1016/S1470-2045(23)00147-X
6. Health Economic Evaluations Alongside Adaptive Platform Trials: A Systematic Review.
Authors: Lee KJY, Huang L, Whitehead C, et al.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2026 Jul
PMID: 41850675
DOI: 10.1016/j.jval.2026.03.001
7. Eclampsia Incidence, Management and Outcomes Across Multi-Country Surveillance Cohorts: Individual Participant Data Meta-Analysis.
Authors: Salvi S, Mandolini D, Bloemenkamp KWM, et al.
Journal: BJOG : an international journal of obstetrics and gynaecology, 2026 Jul
PMID: 41885141
DOI: 10.1111/1471-0528.70216
8. Lenvatinib plus pembrolizumab in participants with advanced or recurrent endometrial cancer: Study 309/KEYNOTE-775 and ENGOT-en9/LEAP-001 post-(neo)adjuvant therapy outcomes.
Authors: Marth C, Lorusso D, Bidziński M, et al.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2026 Jul
PMID: 42167105
DOI: 10.1016/j.ijgc.2026.104693
Authors: Malaza N, Masete M, Adam S, et al.
Journal: International journal of environmental research and public health, 2022 Aug 31
PMID: 36078559
DOI: 10.3390/ijerph191710846
2. Nutritional supplements for preventing preeclampsia: A network meta-analysis.
Authors: Wang C, You C, Zhang Y
Journal: The Indian journal of medical research, 2026 Jul
PMID: 42397815
DOI: 10.25259/IJMR_1582_2025
3. Impact of Oral Sebetralstat on Anxiety Associated With Hereditary Angioedema Attacks.
Authors: Craig T, Aygören-Pürsün E, Bernstein JA, et al.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2026 Jul
PMID: 41786301
DOI: 10.1111/cea.70241
4. ULK1's role in cancer progression and its emerging therapeutic potential.
Authors: Webb JD, Shepherd TG
Journal: Cancer biology & therapy, 2026 Dec 31
PMID: 42308349
DOI: 10.1080/15384047.2026.2680347
5. Adjuvant chemotherapy following chemoradiotherapy as primary treatment for locally advanced cervical cancer versus chemoradiotherapy alone (OUTBACK): an international, open-label, randomised, phase 3 trial.
Authors: Mileshkin LR, Moore KN, Barnes EH, et al.
Journal: The Lancet. Oncology, 2023 May
PMID: 37080223
DOI: 10.1016/S1470-2045(23)00147-X
6. Health Economic Evaluations Alongside Adaptive Platform Trials: A Systematic Review.
Authors: Lee KJY, Huang L, Whitehead C, et al.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2026 Jul
PMID: 41850675
DOI: 10.1016/j.jval.2026.03.001
7. Eclampsia Incidence, Management and Outcomes Across Multi-Country Surveillance Cohorts: Individual Participant Data Meta-Analysis.
Authors: Salvi S, Mandolini D, Bloemenkamp KWM, et al.
Journal: BJOG : an international journal of obstetrics and gynaecology, 2026 Jul
PMID: 41885141
DOI: 10.1111/1471-0528.70216
8. Lenvatinib plus pembrolizumab in participants with advanced or recurrent endometrial cancer: Study 309/KEYNOTE-775 and ENGOT-en9/LEAP-001 post-(neo)adjuvant therapy outcomes.
Authors: Marth C, Lorusso D, Bidziński M, et al.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2026 Jul
PMID: 42167105
DOI: 10.1016/j.ijgc.2026.104693
