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The Rising Burden of Kidney Disease and Emerging Therapies

Inside Nephrology: A Weekly Review

Nefrologia

The Rising Burden of Kidney Disease and Emerging Therapies

This week we examine the rising global burden of chronic kidney disease, explore exciting research on solute carriers and metabolic determinants of autoimmune kidney diseases, and discuss advances in transplant monitoring and targeted therapies.

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Bibliography

1. The updated global burden of chronic kidney disease: one death every 20 seconds.
Authors: Ortiz A, Lees JS, Torra R, et al.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026 Sep 30
PMID: 41739048
DOI: 10.1093/ndt/gfag040


2. The SLC-ome of membrane transport: from molecular discovery to physiology and clinical applications.
Authors: Gyimesi G, Tweedie S, Bruford E, et al.
Journal: Physiological reviews, 2026 Oct 1
PMID: 41026912
DOI: 10.1152/physrev.00001.2024


3. Metabolic determinants of autoimmune kidney diseases.
Authors: Scindia Y, Morel L
Journal: Nature reviews. Nephrology, 2026 Oct
PMID: 42410158
DOI: 10.1038/s41581-026-01096-8


4. Adenine phosphoribosyltransferase deficiency and 2,8-dihydroxyadeninuria.
Authors: Edvardsson VO, Runolfsdottir HL, Palsson R
Journal: Pediatric nephrology (Berlin, Germany), 2026 Oct
PMID: 41820602
DOI: 10.1007/s00467-026-07187-9


5. Normalization of nCounter Gene Expression Data Alters Molecular Diagnostics in Kidney Transplantation.
Authors: Piedrafita A, Sablik M, Preka E, et al.
Journal: Journal of the American Society of Nephrology : JASN, 2026 Oct 1
PMID: 42024462
DOI: 10.1681/ASN.0000001107


6. Clinical Relevance of Donor-Derived Cell-Free DNA in Monitoring Kidney Transplant Rejection.
Authors: Pagliazzi A, Wellekens K, de Loor H, et al.
Journal: Journal of the American Society of Nephrology : JASN, 2026 Oct 1
PMID: 42133430
DOI: 10.1681/ASN.0000001116


7. Belgian recommendations for tissue diagnosis of amyloidosis.
Authors: Dendooven A, Vandendriessche A, Koshy PJ, et al.
Journal: Acta clinica Belgica, 2026 Oct
PMID: 42043894
DOI: 10.1080/17843286.2026.2660739


8. Anti-CD20 monoclonal antibodies in membranous nephropathy.
Authors: Díaz-García JD, Nanwani AC, Navarro AV, et al.
Journal: Nefrologia, 2026 Oct
PMID: 42829227
DOI: 10.1016/j.nefroe.2026.501553


9. Terlipressin in paediatric hepatorenal syndrome-acute kidney injury (HRS-AKI).
Authors: Alexander EC, Wyness B, Moore K, et al.
Journal: Pediatric nephrology (Berlin, Germany), 2026 Oct
PMID: 41711944
DOI: 10.1007/s00467-026-07205-w


10. Circadian Systems and Neural Control of Blood Pressure.
Authors: Aponso HM, Pollock JS, Becker BK, et al.
Journal: Current hypertension reports, 2026 Sep 16
PMID: 42747641
DOI: 10.1007/s11906-026-01390-7

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