Pediatric Frontiers: Weekly Insights
Pediatria
Neonatal and Pediatric Advances: From BPD to PKU
This week's episode covers groundbreaking research in neonatology and pediatrics, including bronchopulmonary dysplasia, PDA management, pediatric VTE, asthma biologics, congenital adrenal hyperplasia, and phenylketonuria.
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Bibliografia
1. Bronchopulmonary dysplasia: A review of pathogenesis and pathophysiology.
Authors: Kalikkot Thekkeveedu R, Guaman MC, Shivanna B
Journal: Respiratory medicine, 2017 Nov
PMID: 29229093
DOI: 10.1016/j.rmed.2017.10.014
2. Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen.
Authors: Gupta S, Subhedar NV, Bell JL, et al.
Journal: The New England journal of medicine, 2024 Jan 25
PMID: 38265644
DOI: 10.1056/NEJMoa2305582
3. Venous thromboembolism in pediatrics: Management of special clinical scenarios.
Authors: Climent FJ, Campo Palacio HJ, Falcón M, et al.
Journal: Anales de pediatria, 2026 Jul
PMID: 42457447
DOI: 10.1016/j.anpede.2026.504234
4. Switching to twice-yearly depemokimab from mepolizumab/benralizumab in severe asthma: a multicenter, randomized, double-blind, phase 3A clinical trial (NIMBLE).
Authors: Chupp G, Nagase H, Skowasch D, et al.
Journal: American journal of respiratory and critical care medicine, 2026 May 1
PMID: 41738176
DOI: 10.1093/ajrccm/aamag031
5. Congenital Adrenal Hyperplasia-Current Insights in Pathophysiology, Diagnostics, and Management.
Authors: Claahsen-van der Grinten HL, Speiser PW, Ahmed SF, et al.
Journal: Endocrine reviews, 2022 Jan 12
PMID: 33961029
DOI: 10.1210/endrev/bnab016
6. Phenylketonuria.
Authors: van Spronsen FJ, Blau N, Harding C, et al.
Journal: Nature reviews. Disease primers, 2021 May 20
PMID: 34017006
DOI: 10.1038/s41572-021-00267-0
Authors: Kalikkot Thekkeveedu R, Guaman MC, Shivanna B
Journal: Respiratory medicine, 2017 Nov
PMID: 29229093
DOI: 10.1016/j.rmed.2017.10.014
2. Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen.
Authors: Gupta S, Subhedar NV, Bell JL, et al.
Journal: The New England journal of medicine, 2024 Jan 25
PMID: 38265644
DOI: 10.1056/NEJMoa2305582
3. Venous thromboembolism in pediatrics: Management of special clinical scenarios.
Authors: Climent FJ, Campo Palacio HJ, Falcón M, et al.
Journal: Anales de pediatria, 2026 Jul
PMID: 42457447
DOI: 10.1016/j.anpede.2026.504234
4. Switching to twice-yearly depemokimab from mepolizumab/benralizumab in severe asthma: a multicenter, randomized, double-blind, phase 3A clinical trial (NIMBLE).
Authors: Chupp G, Nagase H, Skowasch D, et al.
Journal: American journal of respiratory and critical care medicine, 2026 May 1
PMID: 41738176
DOI: 10.1093/ajrccm/aamag031
5. Congenital Adrenal Hyperplasia-Current Insights in Pathophysiology, Diagnostics, and Management.
Authors: Claahsen-van der Grinten HL, Speiser PW, Ahmed SF, et al.
Journal: Endocrine reviews, 2022 Jan 12
PMID: 33961029
DOI: 10.1210/endrev/bnab016
6. Phenylketonuria.
Authors: van Spronsen FJ, Blau N, Harding C, et al.
Journal: Nature reviews. Disease primers, 2021 May 20
PMID: 34017006
DOI: 10.1038/s41572-021-00267-0
