The 99% Conundrum—When High False Positives Drive Life-Saving Precision

Routine neonatal screening is anything but routine. This week, we dive into the data on QTc screening, revealing a startling 95% normalization rate in follow-up cases. We then shift focus to high-priority threats: NICU admissions linked to maternal COVID-19, genetic precision in treating alloimmune thrombocytopenia, and the revolutionary potential of salivary PCR for CMV. We explore how balancing sensitivity vs. specificity and addressing economic disparities are redefining the future of infant health.