Rethinking Diabetes: A Weekly Review
Malattie Metaboliche e Diabetologia
Diabetes Research Updates: From Cold Therapy to Precision Medicine
This week's episode explores groundbreaking diabetes research including cold exposure therapy, cardiovascular outcomes of diabetes medications, SGLT2 inhibitors in monogenic diabetes, and the challenges of diabetes subtyping for precision medicine.
Bibliography
1. Neurovascular Unit Dysfunction and Neural Barrier Pathology in Dysautonomia: Molecular Links to Cardiovascular Autonomic Failure.
Authors: Kordas B, Zglejc-Waszak K, Mizia P, et al.
Journal: International journal of molecular sciences, 2026 Sep 20
PMID: 42794800
DOI: 10.3390/ijms27188375
2. Acute mild cold exposure with shivering reduces 24 h glucose levels in individuals with type 2 diabetes but not prediabetes.
Authors: Hashim D, Jörgensen JA, van de Weijer T, et al.
Journal: Diabetologia, 2026 Oct
PMID: 42474505
DOI: 10.1007/s00125-026-06809-z
3. Clinical, Neuroimaging, and Molecular Characterization of a Juvenile PLAN-like Phenotype in Two Siblings Carrying p.Arg645Gln and an Unresolved Exon 4-7 Copy-Number Gain: A Case Report.
Authors: Janeczko-Czarnecka M, Gręda M, Cichosz D, et al.
Journal: Genes, 2026 Sep 16
PMID: 42793026
DOI: 10.3390/genes17091132
4. Type 2 diabetes subtypes for precision medicine: methodological challenges and alternative prediction-based approaches.
Authors: Mori T, Herder C, Cardoso P, et al.
Journal: Diabetologia, 2026 Oct
PMID: 42502138
DOI: 10.1007/s00125-026-06802-6
5. Patient-reported outcomes in adults with type 3c diabetes: a scoping review across aetiologies and pancreatic resection extent.
Authors: Meden A, Kravos Tramšek NA
Journal: Frontiers in endocrinology, 2026
PMID: 42807226
DOI: 10.3389/fendo.2026.1963887
6. A narrative review of what cohorts have taught us and how they have laid the foundation for much of our understanding of type 2 diabetes.
Authors: Kim SH, Arora I, Agyemang C, et al.
Journal: Diabetologia, 2026 Oct
PMID: 42644887
DOI: 10.1007/s00125-026-06812-4
7. Effect of Medications for Type 2 Diabetes on Cardiovascular Events and Mortality: A Comprehensive Pairwise and Network Meta-Analysis.
Authors: Silverii GA, Velardi V, Marinelli C, et al.
Journal: Diabetes, obesity & metabolism, 2026 Oct
PMID: 42530338
DOI: 10.1111/dom.71128
8. The Role of Immunological Challenges, Oxidative Stress, and Dietary Interventions in Managing Hashimoto's Thyroiditis: A Narrative Review.
Authors: Morasiewicz-Jeziorek J, Buczyńska A, Krętowski AJ, et al.
Journal: Nutrition reviews, 2026 Oct 1
PMID: 41498438
DOI: 10.1093/nutrit/nuaf195
9. Delayed Diagnosis of Type 1 Gaucher Disease at Age 15 After Years of Mild Cytopenias and Splenomegaly: A Case Report and Long-Term Follow-Up.
Authors: Muras-Szwedziak K, Kasznicki J, Wegner O, et al.
Journal: The American journal of case reports, 2026 Sep 10
PMID: 42721115
DOI: 10.12659/AJCR.952793
10. Glycemic and Renal Effects of SGLT2 Inhibitors in Monogenic Diabetes: A Real-World National Study.
Authors: Audrain E, Bel Lassen P, Bellanné-Chantelot C, et al.
Journal: Diabetes, obesity & metabolism, 2026 Oct
PMID: 42559753
DOI: 10.1111/dom.71169
Authors: Kordas B, Zglejc-Waszak K, Mizia P, et al.
Journal: International journal of molecular sciences, 2026 Sep 20
PMID: 42794800
DOI: 10.3390/ijms27188375
2. Acute mild cold exposure with shivering reduces 24 h glucose levels in individuals with type 2 diabetes but not prediabetes.
Authors: Hashim D, Jörgensen JA, van de Weijer T, et al.
Journal: Diabetologia, 2026 Oct
PMID: 42474505
DOI: 10.1007/s00125-026-06809-z
3. Clinical, Neuroimaging, and Molecular Characterization of a Juvenile PLAN-like Phenotype in Two Siblings Carrying p.Arg645Gln and an Unresolved Exon 4-7 Copy-Number Gain: A Case Report.
Authors: Janeczko-Czarnecka M, Gręda M, Cichosz D, et al.
Journal: Genes, 2026 Sep 16
PMID: 42793026
DOI: 10.3390/genes17091132
4. Type 2 diabetes subtypes for precision medicine: methodological challenges and alternative prediction-based approaches.
Authors: Mori T, Herder C, Cardoso P, et al.
Journal: Diabetologia, 2026 Oct
PMID: 42502138
DOI: 10.1007/s00125-026-06802-6
5. Patient-reported outcomes in adults with type 3c diabetes: a scoping review across aetiologies and pancreatic resection extent.
Authors: Meden A, Kravos Tramšek NA
Journal: Frontiers in endocrinology, 2026
PMID: 42807226
DOI: 10.3389/fendo.2026.1963887
6. A narrative review of what cohorts have taught us and how they have laid the foundation for much of our understanding of type 2 diabetes.
Authors: Kim SH, Arora I, Agyemang C, et al.
Journal: Diabetologia, 2026 Oct
PMID: 42644887
DOI: 10.1007/s00125-026-06812-4
7. Effect of Medications for Type 2 Diabetes on Cardiovascular Events and Mortality: A Comprehensive Pairwise and Network Meta-Analysis.
Authors: Silverii GA, Velardi V, Marinelli C, et al.
Journal: Diabetes, obesity & metabolism, 2026 Oct
PMID: 42530338
DOI: 10.1111/dom.71128
8. The Role of Immunological Challenges, Oxidative Stress, and Dietary Interventions in Managing Hashimoto's Thyroiditis: A Narrative Review.
Authors: Morasiewicz-Jeziorek J, Buczyńska A, Krętowski AJ, et al.
Journal: Nutrition reviews, 2026 Oct 1
PMID: 41498438
DOI: 10.1093/nutrit/nuaf195
9. Delayed Diagnosis of Type 1 Gaucher Disease at Age 15 After Years of Mild Cytopenias and Splenomegaly: A Case Report and Long-Term Follow-Up.
Authors: Muras-Szwedziak K, Kasznicki J, Wegner O, et al.
Journal: The American journal of case reports, 2026 Sep 10
PMID: 42721115
DOI: 10.12659/AJCR.952793
10. Glycemic and Renal Effects of SGLT2 Inhibitors in Monogenic Diabetes: A Real-World National Study.
Authors: Audrain E, Bel Lassen P, Bellanné-Chantelot C, et al.
Journal: Diabetes, obesity & metabolism, 2026 Oct
PMID: 42559753
DOI: 10.1111/dom.71169
